Online Certificate Courses in Reproductive Genetics & Reproductive Immunology
A Joint Certification by TAPISAR & SCALE
(Sri Chakra Academy for Learning & Education)
Advanced Certificate Courses
Join our expert-led online courses in reproductive genetics and immunology for professionals.
Reproductive Genetics
Explore structured modules and case discussions in reproductive genetics for clinicians and lab professionals.
Reproductive Immunology
Gain insights through interactive sessions in reproductive immunology tailored for healthcare experts.
Joint Certification issued by TAPISAR & SCALE enhance your academic credentials and professional growth.
Certification Value
Course Fee Rs10,000/-
Course Fee Rs10,000/-
Why Join Us
Our certificate courses blend expert-led teaching, case-based discussions, and practical insights to bridge the gap between theory and real-world fertility practice. Whether in genetics or immunology, you’ll gain the knowledge and skills to deliver advanced, evidence-based care in reproductive medicine.
About Us
SCALE (Sri Chakra Academy for Learning & Education), the academic arm of Sri Chakra Fertility, is dedicated to advancing education in Assisted Reproductive Technology (ART). Through certificate programs, workshops, and training modules, SCALE has successfully trained clinicians, embryologists, and researchers across India, combining evidence-based teaching, hands-on learning, and expert mentorship.
TAPISAR (Tamil Nadu and Pondicherry Chapter of the Indian Society for Assisted Reproduction.) is a professional body committed to promoting excellence, research, and collaboration in reproductive medicine. With a strong academic foundation and a network of experts, TAPISAR has been at the forefront of creating platforms for continuous medical education.
Together, SCALE and TAPISAR bring unmatched expertise and credibility to specialized certificate courses in Reproductive Genetics and Reproductive Immunology, empowering healthcare professionals with advanced knowledge and clinical application to enhance fertility care outcomes.
CERTIFICATE COURSE IN GENETICS IN INFERTILITY
12 MODULES- 12 WEEKS
Genetics in Infertility – Principles, Diagnostics, and Clinical Applications
Course duration:3 months
Target Audience:
Postgraduate students in reproductive medicine, embryology, genetics ; practicing clinicians; laboratory personnel in IVF/genetics
Course Objectives
By the end of the course, students will:
1. Understand the genetic basis of male and female infertility.
2. Acquire knowledge of molecular and cytogenetic testing methods.
3. Interpret genetic testing results in the context of infertility.
4. Understand the clinical implications for reproductive counselling and ART.
Module 1: Introduction to Genetics in Reproduction
• Overview of human genetics & inheritance patterns
• Gametogenesis & meiotic errors
• Chromosomal abnormalities and reproductive outcomes
• Genetic epidemiology of infertility
Module 2: Laboratory Techniques in Reproductive Genetics
• Karyotyping & FISH in infertility workup
• PCR, qPCR, MLPA, and Sanger sequencing
• Next-generation sequencing (NGS) workflows
• SNP microarrays and CNV analysis
Practical Demo: Karyotype analysis & interpretation
Module 3: Genetics of Male Infertility
• Y chromosome microdeletions (AZF regions)
• Klinefelter syndrome & other sex chromosome aneuploidies
• CFTR mutations and congenital bilateral absence of vas deferens (CBAVD) • Spermatogenic failure – monogenic causes
• Sperm DNA fragmentation & epigenetic alterations
Case Discussion: Interpretation of Yq microdeletion PCR report
Module 4: Genetics of Female Infertility
• Disorders of sexual development - Turner syndrome & sex chromosome abnormalities • Primary ovarian insufficiency – genetic causes (FMR1 premutation, BMP15, FOXL2) • Endometriosis – GWAS findings & hereditary aspects
• Mitochondrial DNA disorders and ovarian reserve
Case Discussion: Genetic workup in premature ovarian insufficiency
Module 5: Genetic Risk Management in ART Clinics
• Carrier screening panels for donor and patient selection
• Handling incidental findings
• Genetic implications in donor pregnancies
Case based Scenarios: Selecting a carrier screening panel – targeted versus comprehensive approach.
Module 6: Prenatal Genetic Diagnosis
• Prenatal Screening
• Non invasive Prenatal Screening (NIPT)
• Invasive Prenatal Diagnosis
• Prenatal screening options in ART pregnancies.
Case Discussion: Case series on Prenatal finding, Genetic investigations employed, result interpretation and Clinical decision making
Module 7: Preimplantation Genetic Testing
• Principles of PGT-A
• Indications for genetic testing in ART
• Biopsy techniques & NGS-based embryo testing
• Mitoscore and its relevance
• Mosaicism & its clinical interpretation
• Advances in PGT-A
Case Discussion: Data interpretation from a PGT-A report, Implantation failure after transfer of euploid embryo
Module 8: Preimplantation Genetic Testing
• Principles of PGT-SR
• PGT-M – Indications, evaluations, Pre PGT workup
• Do we need to add PGT-A along with PGT-M?
• Interpreting PGT-M reports
• Advances in PGT-M
Case Discussion: Embryo transfer decision making based on PGT-M report
Module 9: Genetics of Recurrent Pregnancy Loss (RPL)
• Aneuploidy, mosaicism, and recurrent miscarriage
• Products of conception (POC) genetic analysis – karyotyping, CMA, NGS
• Genetic investigations in couples experiencing RPL
• Role of PGT in preventing recurrence – is it useful?
• Case Review: Management of Parental chromosomal rearrangement carriers
Module 10: Genetics of Recurrent Implantation Failure (RIF)
• Genetic and chromosomal factors in RIF – mechanism
• Embryo-related causes: aneuploidy, mosaicism, segmental abnormalities • Endometrial receptivity
• Role of PGT, Endometrial receptivity, and molecular microbiome assessment
• Clinical decision-making after repeated failed transfers
Case Review: Embryo selection and transfer strategy in RIF patients
Module 11: Genetic Counselling in Infertility
• Structuring a genetic counselling session in the ART clinic
• Pedigree construction & risk assessment
• Communicating results to couples
• Explaining complex reports to patients in lay language
• Managing patient expectations & ethical dilemmas
• Local and international guidelines (ICMR, ESHRE, ASRM)Ethical issues in genetic testing for infertility
• Reproductive options & decision-making
• Regulatory guidelines (ICMR, ESHRE, ASRM)
Role-play Activity: Counselling a couple with male factor infertility, Counselling after a mosaic embryo result, Counselling for PGT-M
Module 12: Lab aspects of PGT
● Lab preparation
● Medi and consumables required
● Techniques of embryo biopsy
● Handling of embryos and specimens
● Tubing techniques for ideal results
● Shipping of cells and filling forms
● Consents to be signed
CERTIFICATE COURSE IN
REPRODUCTIVE IMMUNOLOGY
5 MODULES- 08 WEEKS
Course Duration: 8 weeks
Format: Online (live interactive lectures, case discussions, assessments)
Target Audience: Fertility specialists, gynecologists, embryologists, postgraduates and fellowship students, researchers in reproductive medicine
Module 1: Fundamentals of Reproductive Immunology (Weeks 1–2)
● Introduction to reproductive immunology – scope & clinical importance
● Maternal immune tolerance in pregnancy – mechanisms & key players
● Innate vs adaptive immunity in reproduction
● Endometrial receptivity and immune modulation
● Key immune cells: NK cells, Tregs, macrophages, dendritic cells
● Cytokine balance (Th1/Th2/Th17, IL-10, TNF-α, IFN-γ)
Module 2: Immunological Basis of Reproductive Disorders (Weeks 3–4)
● Recurrent implantation failure (RIF) and immune causes
● Recurrent pregnancy loss (RPL) and immune dysregulation
● Endometriosis and autoimmunity in infertility
● PCOS and low-grade inflammation
● Preeclampsia and immune maladaptation
● Immunogenetics in reproduction (HLA, KIR genes, alloimmunity)
Module 3: Investigations in Reproductive Immunology (Weeks 5)
● Overview of available tests & their evidence levels
● Peripheral blood NK cell count & activity assays
● Uterine NK cells – biopsy & immunohistochemistry
● Cytokine profiling
● Th1/Th2 balance testing
● HLA/KIR typing and significance
● Pitfalls, controversies & interpretation of results
Module 4: Immunomodulatory Therapies in ART (Weeks 6-7)
● Role of corticosteroids in ART & pregnancy
● Heparin and aspirin in reproductive immunology
● Intravenous immunoglobulin (IVIG) – indications & evidence
● Intralipids – mechanism, protocols, controversies
● G-CSF (systemic and intrauterine use)
● Tacrolimus, sirolimus, and biologics (emerging therapies)
● Lifestyle, nutrition, and immune modulation
Module 5: Translational & Clinical Application (Week 8)
● Case-based discussions:
o RIF with elevated NK cells
o RPL with alloimmune imbalance
o Endometriosis-related immune dysfunction
● Critical appraisal of evidence – what is proven vs experimental
● Personalized medicine in reproductive immunology
● Future directions: microbiome, immunogenetics, AI in immunology
● Ethical and safety considerations in immunotherapy